TY - Generic T1 - Dynamic querying for pattern identification in microarray and genomic data T2 - 2003 International Conference on Multimedia and Expo, 2003. ICME '03. Proceedings Y1 - 2003 A1 - Hochheiser, H. A1 - Baehrecke, E. H. A1 - Stephen M. Mount A1 - Shneiderman, Ben KW - Bioinformatics KW - data sets KW - Displays KW - dynamic querying KW - expression profiles KW - Frequency KW - Gene expression KW - genes KW - Genetics KW - genomic data KW - Genomics KW - linear ordered sequences KW - macromolecules KW - medical signal processing KW - Mice KW - Microarray KW - pattern identification KW - pattern recognition KW - premRNA splicing KW - Query processing KW - sequences KW - Signal processing KW - splicing KW - TimeSearcher AB - Data sets involving linear ordered sequences are a recurring theme in bioinformatics. Dynamic query tools that support exploration of these data sets can be useful for identifying patterns of interest. This paper describes the use of one such tool - timesearcher - to interactively explore linear sequence data sets taken from two bioinformatics problems. Microarray time course data sets involve expression levels for large numbers of genes over multiple time points. Timesearcher can be used to interactively search these data sets for genes with expression profiles of interest. The occurrence frequencies of short sequences of DNA in aligned exons can be used to identify sequences that play a role in the pre-mRNA splicing. Timesearcher can be used to search these data sets for candidate splicing signals. JA - 2003 International Conference on Multimedia and Expo, 2003. ICME '03. Proceedings PB - IEEE VL - 3 SN - 0-7803-7965-9 ER -