CBCB Seminar Series

Most CBCB seminars are held from 2 p.m. until 3:15 p.m. on Thursdays in the CBCB seminar room, 3118 at Biomolecular Sciences Building #296
Some external seminars are listed here. These, and some other exceptions, will have a different time and/or place.
For directions to CBCB please scroll down.

2:00 p.m. Thursday, Feb. 11, 2010

Title: HMMER: a new generation of homology search software

By: Sean Eddy, Janelia Farm Research Campus, Howard Hughes Medical Institute

Venue: 1103 Biosciences Research Bldg.

Abstact: Database homology searching might be the most important application in computational molecular biology, and since the 1990s, BLAST has been our main workhorse. Since BLAST's introduction, theoretical advances have been made in applying probabilistic inference methods to homology searches using hidden Markov model (HMM) approaches. General adoption of probabilistic methods has been limited by some key problems, including the fact that the popular HMM implementations (including my HMMER software) are computationally demanding. I will talk about HMMER3, a new generation of HMMER that aims to even more fully deploy probabilistic inference technology on homology searches, while at the same time attaining (and perhaps soon surpassing) BLAST's speed.

Speaker: Sean Eddy is a group leader at Janelia Farm.
Bio
Web page

Scheduled Events

  • Feb. 11, 2010: Sean Eddy, HHMI Janelia Farm
  • April 8, 2010: Olga Troyanskaya, Princeton, "From genomics data integration to using functional relationship networks to understand disease at the molecular level"
  • upcoming: Mei-Ling Ting Lee, Maryland School of Public Health

Past Events


Other Events


Directions

More detailed transportation options to CBCB can be found here.

From the Capital Beltway to Parking Lot:
  • take Capital Beltway (I-495) Exit 25 and turn onto Baltimore Avenue (US Route 1) South
  • go two miles south on Baltimore Ave and enter the main gate at Campus Drive
  • take the right lane into campus and make first right turn onto Paint Branch Drive
  • stop at the first stop sign then pass Stadium Drive on the left
  • stop at the second stop sign then pass Parking Lot XX2 on the right
  • look for the Paint Branch Drive Visitor Lot on the left
  • turn left onto Technology Drive and park in the Paint Branch Drive Visitor Lot


From Parking Lot to CBCB:
  • the back of the Biomolecular Sciences Building #296 faces this parking lot
  • walk around to the front of the building and using the keypad near the front door
  • dial the number of one of the CBCB staff members in order to gain entrance to the building
  • CBCB is located on the third floor of the Biomolecular Sciences Building #296