Alignment and clustering of phylogenetic markers - implications for microbial diversity studies
| Title | Alignment and clustering of phylogenetic markers - implications for microbial diversity studies |
| Publication Type | Journal Articles |
| Year of Publication | 2010 |
| Authors | White JR, Navlakha S, Nagarajan N, Ghodsi M-R, Kingsford C, Pop M. |
| Journal | BMC BioinformaticsBMC Bioinformatics |
| Volume | 11 |
| Type of Article | 10.1186/1471-2105-11-152 |
| ISBN Number | 1471-2105 |
| Abstract | Molecular studies of microbial diversity have provided many insights into the bacterial communities inhabiting the human body and the environment. A common first step in such studies is a survey of conserved marker genes (primarily 16S rRNA) to characterize the taxonomic composition and diversity of these communities. To date, however, there exists significant variability in analysis methods employed in these studies. |