CBCB Research in Progress Series (RIPS)

UPDATE (Jan. 24, 2022): For Spring 2022, CBCB RIP Seminars will be held virtually. Unless otherwise noted, they will take place on Thursday afternoons and the talks will be streamed remotely via Zoom. The format for the RIPS talks will be the same as in previous semesters; each week we will look to have 2 30-minute talks. However, if you feel you need an hour slot, please specify this in the second row of the corresponding date on the spreadsheet. The signup sheet for this semester is here. The day and time for the RIPS seminar this semester will be Thursdays from 2-3PM. For Zoom meeting details to view RIP talks contact Barbara Lewis.

The CBCB RIP series provides an informal forum for computational biologists to keep abreast of colleagues' projects, to help students and postdocs hone their presentation skills, and to get expert feedback on new or ongoing projects. The forum is targeted towards anyone working at the interface of Biology and Analytical sciences. This is a great opportunity for everyone in our CBCB community to come together, and to learn about the research being done by our colleagues in different labs within the center.

Other seminars you may be interested in attending can be found HERE

    CBCB RIPS Schedule for Spring Semester 2022




    Topic & Abstract

    Time (if other than 2PM)


    Mikhail Kolmogorov

    New Investigator at NCI

    Algorithms for genome and metagenome assembly using long reads

    Abstract: Long-read sequencing technologies have substantially improved our ability to study large and complex genomes. However, de novo assembly of complex genomic and metagenomic datasets remains difficult. In this talk, I will give an algorithmic overview of the genome assembly problem. I will also highlight our Flye assembler that uses repeat graphs to generate accurate and complete assemblies. Finally, I will also present our new metagenomic assembler metaFlye, which addresses important long-read metagenomic assembly challenges, such as uneven bacterial composition and intra-species heterogeneity. Using metaFlye, we were able to recover complete or nearly-complete bacterial genomes from complex environmental samples, such as human gut or cow rumen. We also showed that long-read assembly of human microbiomes enables the discovery of full-length biosynthetic gene clusters that encode biomedically important natural products.




    Dr. Laura Dillon

    Invited industry speaker - Parthenon Therapeutics (Alum - El-Sayed Lab)






    Spring Break - No RIPS