Publications
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2004. X-ray crystal structure of the hypothetical phosphotyrosine phosphatase MDP-1 of the haloacid dehalogenase superfamily. BiochemistryBiochemistry. 43
2012. Whole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity. PLoS neglected tropical diseasesPLoS neglected tropical diseases. 6
2012. Whole genome analysis of Leptospira licerasiae provides insight into leptospiral evolution and pathogenicity.. PLoS Negl Trop Dis. 6(10):e1853.
1983. The U1 small nuclear RNA-protein complex selectively binds a 5' splice site in vitro.. Cell. 33(2):509-18.
2013. Three independent determinants of protein evolutionary rate. J Mol EvolJ Mol EvolJ Mol Evol. 76:98-111.
1973. Surgery of the hip and knee in patients with rheumatoid arthritis.. J Bone Joint Surg Am. 55(2):301-14.
1982. Structure and function of small ribonucleoproteins from eukaryotic cells.. Princess Takamatsu Symp. 12:101-7.
1990. Structure and expression of the Drosophila melanogaster gene for the U1 small nuclear ribonucleoprotein particle 70K protein.. Mol Cell Biol. 10(6):2492-502.
2014. Stable isotope labeling of phosphoproteins for large-scale phosphorylation rate determination.. Mol Cell Proteomics. 13(4):1106-18.
1983. Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein.. Cell. 35(1):101-7.
2007. SplicePort--an interactive splice-site analysis tool.. Nucleic Acids Res. 35(Web Server issue):W285-91.
1993. Species-specific signals for the splicing of a short Drosophila intron in vitro.. Mol Cell Biol. 13(2):1104-18.
1983. Small ribonucleoproteins from eukaryotes: structures and roles in RNA biogenesis.. Cold Spring Harb Symp Quant Biol. 47 Pt 2:893-900.
1981. Sequence of U1 RNA from Drosophila melanogaster: implications for U1 secondary structure and possible involvement in splicing.. Nucleic Acids Res. 9(23):6351-68.
1983. Pseudogenes for human small nuclear RNA U3 appear to arise by integration of self-primed reverse transcripts of the RNA into new chromosomal sites.. Cell. 32(2):461-72.
2009. Protein quantification across hundreds of experimental conditions.. Proc Natl Acad Sci U S A. 106(37):15544-8.
2013. Primate transcript and protein expression levels evolve under compensatory selection pressures.. Science. 342(6162):1100-4.
2011. Predicting selective drug targets in cancer through metabolic networks.. Mol Syst Biol. 7:501.
2014. Predicting cancer-specific vulnerability via data-driven detection of synthetic lethality.. Cell. 158(5):1199-209.
2014. Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer.. Elife. 3
2012. The partitioned LASSO-patternsearch algorithm with application to gene expression data. BMC bioinformaticsBMC Bioinformatics. 13
2001. MDP-1 is a new and distinct member of the haloacid dehalogenase family of aspartate-dependent phosphohydrolases. BiochemistryBiochemistry. 40
1989. Management of an enlarging aortic aneurysm in the presence of radiation induced retroperitoneal fibrosis.. J Cardiovasc Surg (Torino). 30(2):233-5.