High performance computing


Bayesian tool to integrate genetic and epigenetic data to find causal expression regulatory polymorphisms


Algorithms for the Analysis of Data from Massively-parallel Genome Sequencing

New generation DNA sequencing technologies are revolutionizing modern biological research. Scientists can now generate the rough equivalent of an entire human genome (~3 billion base-pairs of DNA) in just a few days with one single sequencing instrument. Until recently, such amounts of data could only be generated at large genome centers using hundreds of sequencers. The analysis of these data is complicated by their size - a single run of a sequencing instrument yields terabytes of information, often requiring a significant scale-up of the existing computational infrastructure.

Principal Investigators

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