Publications

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2017
Venkateswaran K, Checinska-Sielaff A, Klubnik J, Treangen T, Rosovitz M.J., Bergman NH.  2017.  Draft Genome Sequences from a Novel Clade of Bacillus cereus sensu lato Strains Isolated from the International Space Station. Genome Announcements. 1:1.
2016
Auslander N, Wagner A, Oberhardt M, Ruppin E.  2016.  Data-Driven Metabolic Pathway Compositions Enhance Cancer Survival Prediction. PLOS Computational Biology. 12(9):e1005125.
Mazza A, Wagner A, Ruppin E, Sharan R.  2016.  Functional Alignment of Metabolic Networks.. J Comput Biol.
tyläinen Tö, Jerby L, jä EM ä, Mattila I, ntti Sä, Auvinen P, Gastaldelli A, rvinen Hä, Ruppin E, ič Mš.  2016.  Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease. Nature Communications. 7:8994.
tyläinen Tö, Jerby L, jä EM ä, Mattila I, ntti Sä, Auvinen P, Gastaldelli A, rvinen Hä, Ruppin E, ič Mš.  2016.  Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease. Nature Communications. 7:8994.
Hyötyläinen T, Jerby L, Petäjä EM, Mattila I, Jäntti S, Auvinen P, Gastaldelli A, Yki-Järvinen H, Ruppin E, Orešič M.  2016.  Genome-scale study reveals reduced metabolic adaptability in patients with non-alcoholic fatty liver disease.. Nat Commun. 7:8994.
Auslander N, Yizhak K, Weinstock A, Budhu A, Tang W, Wang XWei, Ambs S, Ruppin E.  2016.  A joint analysis of transcriptomic and metabolomic data uncovers enhanced enzyme-metabolite coupling in breast cancer.. Sci Rep. 6:29662.
Shaked I, Oberhardt  A., Atias N, Sharan R, Ruppin E.  2016.  Metabolic Network Prediction of Drug Side Effects. Cell Systems. 2(3):209-213.
Mokryn O, Wagner A, Blattner M, Ruppin E, Shavitt Y.  2016.  The Role of Temporal Trends in Growing Networks.. PLoS One. 11(8):e0156505.
Oberhardt MA, Zarecki R, Reshef L, Xia F, Duran-Frigola M, Schreiber R, Henry CS, Ben-Tal N, Dwyer DJ, Gophna U et al..  2016.  Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5'-Phosphate Production in E. coli.. PLoS Comput Biol. 12(1):e1004705.
Oberhardt MA, Zarecki R, Reshef L, Xia F, Duran-Frigola M, Schreiber R, Henry CS, Ben-Tal N, Dwyer DJ, Gophna U et al..  2016.  Systems-Wide Prediction of Enzyme Promiscuity Reveals a New Underground Alternative Route for Pyridoxal 5'-Phosphate Production in E. coli.. PLoS Comput Biol. 12(1):e1004705.
Pozniak Y, Balint-Lahat N, Rudolph JDaniel, Lindskog C, Katzir R, Avivi C, Pontén F, Ruppin E, Barshack I, Geiger T.  2016.  System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.. Cell Syst. 2(3):172-84.
Pozniak Y, Balint-Lahat N, Rudolph JDaniel, Lindskog C, Katzir R, Avivi C, Pontén F, Ruppin E, Barshack I, Geiger T.  2016.  System-wide Clinical Proteomics of Breast Cancer Reveals Global Remodeling of Tissue Homeostasis.. Cell Syst. 2(3):172-84.
Cunningham CE, Li S, Vizeacoumar FS, Bhanumathy KKalyanasun, Lee JSang, Parameswaran S, Furber L, Abuhussein O, Paul JM, McDonald M et al..  2016.  Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget.
2015
Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D et al..  2015.  Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature. 527(7578):379-383.
Rabinovich S, Adler L, Yizhak K, Sarver A, Silberman A, Agron S, Stettner N, Sun Q, Brandis A, Helbling D et al..  2015.  Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature. 527(7578):379-383.
Wagner A, Cohen N, Kelder T, Amit U, Liebman E, Steinberg DM, Radonjic M, Ruppin E.  2015.  Drugs that reverse disease transcriptomic signatures are more effective in a mouse model of dyslipidemia.. Mol Syst Biol. 11(3):791.
Wagner A, Cohen N, Kelder T, Amit U, Liebman E, Steinberg DM, Radonjic M, Ruppin E.  2015.  Drugs that reverse disease transcriptomic signatures are more effective in a mouse model of dyslipidemia.. Mol Syst Biol. 11(3):791.
Uziel O, Yosef N, Sharan R, Ruppin E, Kupiec M, Kushnir M, Beery E, Cohen-Diker T, Nordenberg J, Lahav M.  2015.  The effects of telomere shortening on cancer cells: a network model of proteomic and microRNA analysis.. Genomics. 105(1):5-16.
Pop M.  2015.  Encyclopedia of MetagenomicsHuman Microbiome, Assembly and Analysis Software, Project. :243-246.
Rangarajan N, Kulkarni P, Hannenhalli S.  2015.  Evolutionarily conserved network properties of intrinsically disordered proteins.. PLoS One. 10(5):e0126729.
Ish-Am O, Kristensen DM, Ruppin E.  2015.  Evolutionary Conservation of Bacterial Essential Metabolic Genes across All Bacterial Culture Media. PLOS ONE. 10(4):e0123785.
Zheng L, Cardaci S, Jerby L, MacKenzie ED, Sciacovelli M, T Johnson I, Gaude E, King A, Leach JDG, Edrada-Ebel RA et al..  2015.  Fumarate induces redox-dependent senescence by modifying glutathione metabolism.. Nat Commun. 6:6001.
Tardito S, Oudin ïs, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen Ø, Weinstock A, Wagner A et al..  2015.  Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. Nature Cell Biology. 17(12):1556-1568.
Tardito S, Oudin ïs, Ahmed SU, Fack F, Keunen O, Zheng L, Miletic H, Sakariassen Ø, Weinstock A, Wagner A et al..  2015.  Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma. Nature Cell Biology. 17(12):1556-1568.

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